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Home Antibody All anti-FASN antibodies

Anti-FASN Antibody

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SKU Description Amount Price Availability*  
TA308751
  • Rabbit Polyclonal antibody to Fatty Acid Synthase (fatty acid synthase)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418211) , 20ug Explanation
100ul $325 3-7 Days
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WB(2)
IHC(1)
IF(2)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 401 and 694 of Fatty Acid Synthase (Uniprot ID#P49327)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Rat, Bovine) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 273kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rat (85%), Bovine (81%)

Reference Data

Target NameHomo sapiens fatty acid synthase (FASN)
Alternative NameFAS; OA-519; SDR27X1
Database LinkNP_004095
Entrez Gene 2194 Human
Entrez Gene 14104 Mouse
Entrez Gene 50671 Rat
FunctionThe enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq]
Related PathwayDruggable Genome Fatty acid biosynthesisMetabolic pathwaysInsulin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (50 ug of whole cell lysate). A: mouse liver. 5% SDS PAGE. TA308751 diluted at 1:1000.
WB Image
Sample (30 ug of whole cell lysate). A: Molt-4 . 5% SDS PAGE. TA308751 diluted at 1:1000
IHC Image
Immunohistochemical analysis of paraffin-embedded OECM1 xenograft, using Fatty Acid Synthase(TA308751) antibody at 1:500 dilution.
IF Image
Fatty Acid Synthase antibody [N1N2], N-term detects Fatty Acid Synthase protein at cytoplasm by immunofluorescent analysis. Sample: 293T cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Fatty Acid Synthase protein stained by Fatty Acid Syn
IF Image
Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using Fatty Acid Synthase(TA308751) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:2000.

 

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