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Also for RAD9A (NM_004584)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 197 and 361 of Rad9|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens RAD9 homolog A (S. pombe) (RAD9A), transcript variant 1|
|This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene. [provided by RefSeq]|
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A: A431 B: Hela (anti-RAD9A antibody diluted at 1:1000)
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Rad9 (anti-RAD9A antibody) antibody at 1:100 dilution.