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Home Antibody All anti-AXIN1 antibodies

Anti-AXIN1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308745
  • Rabbit polyclonal antibody to Axin 1 (axin 1)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418638) , 20ug
100ul 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenSynthetic peptide contain a sequence corresponding to a region within amino acids 800 and 862 of Human AXIN1
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.76mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens axin 1 (AXIN1), transcript variant 1
Alternative NameAXIN; PPP1R49
Database LinkNP_003493
FunctionThis gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein), beta 1, 88kDa, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
Related Pathway
TGF Beta Signaling Pathway
Wnt Signaling Pathway

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WB Image
Sample(30 ug of whole cell lysate) A:A431 B:H1299 (anti-AXIN1 antibody diluted at 1:1500

 

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