Home Antibody All anti-PRKD2 antibodies
Also for PRKD2 (NM_001079882)
|Recombinant fragment corresponding to a region within amino acids 529 and 862 of PKD2 (Uniprot ID#Q9BZL6)|
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (100%)
|Homo sapiens protein kinase D2 (PRKD2), transcript variant 4|
|HSPC187; nPKC-D2; PKD2|
Entrez Gene 25865 Human
|The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]|
|Protein KinaseDruggable Genome |
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Sample (30 ug of whole cell lysate). A: Molt-4 . 7.5% SDS PAGE. TA308724 diluted at 1:1000.
PKD2 antibody [C1C3] detects PKD2 protein at cytosol and membrane on human breast carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. PKD2 antibody [C1C3] (TA308724) dilution: 1:500.
PKD2 antibody [C1C3] detects PKD2 protein at cytosol and membrane on mouse intestine by immunohistochemical analysis. Sample: Paraffin-embedded mouse intestine. PKD2 antibody [C1C3] (TA308724) dilution: 1:500.
PKD2 antibody [C1C3] detects PKD2 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: PKD2 protein stained by PKD2 antibody [C1C3] (TA308724) diluted at 1:200. Blue: Hoechst 33342 staining.