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Home Antibody All anti-YWHAB antibodies

Anti-YWHAB Antibody

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SKU Description Amount Price Availability*  
TA308715 Rabbit Polyclonal antibody to 14-3-3 beta (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide) 100ul $325 In Stock
LC418677 YWHAB HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(2)
IHC(1)
IF(1)
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Also for YWHAB (NM_003404)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 171 of 14-3-3 beta (Uniprot ID#P31946)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Rhesus Monkey, Bovine) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:5000-1:20000
Predicted MW Explanation 28kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rhesus Monkey (100%), Bovine (100%)

Reference Data

Target NameHomo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta (YWHAB), transcript variant 1
Alternative NameGW128; HEL-S-1; HS1; KCIP-1; YWHAA
Database LinkNP_003395
Entrez Gene 7529 Human
Entrez Gene 717788 Monkey
FunctionThis gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq]
Related PathwayDruggable Genome Cell cycleOocyte meiosisNeurotrophin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (20 ug of whole cell lysate). A: mouse brain. 12% SDS PAGE. TA308715 diluted at 1:10000.
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Sample (30 ug of whole cell lysate). A: A431 . B: H1299. C: Hela. D: Hep G2 . E: Molt-4 . F: Raji. 12% SDS PAGE. TA308715 diluted at 1:10000.
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Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using 14-3-3 beta(TA308715) antibody at 1:500 dilution.
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Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using 14-3-3 beta (TA308715) antibody at 1:200 dilution.
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