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Home Antibody All anti-PAX8 antibodies

Anti-PAX8 Antibody

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SKU Description Amount Price Availability*  
TA308698 Rabbit polyclonal antibody to PAX8CC (paired box 8) 100ul $325 3-7 Days
LC429402 PAX8 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IP(1)
IHC(1)
IF(1)
Assay(1)

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 204 of PAX8
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, Assay, IHC, IF, IP Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 43kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens paired box 8 (PAX8), transcript variant PAX8E
Alternative NameOTTHUMP00000158659; OTTHUMP00000158660; paired domain gene 8; paired box 8
Database LinkNP_054698
Entrez Gene 7849 Human
FunctionThis gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternateively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]
Related PathwayTranscription FactorsDruggable Genome Pathways in cancerThyroid cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample(30 ug whole cell lysate). A:293T. 10% SDS PAGE. TA308698 diluted at 1:1000
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PAX8 antibody immunoprecipitates PAX8 protein-DNA in ChIP experiments. ChIP Sample: 293T whole cell lysate/extract A. 5 ug preimmune rabbit IgG B. 5 ug of PAX8 antibody (TA308698) The precipitated DNA was detected by PCR with primer set targeting to E2F1
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PAX8 antibody detects PAX8 protein at nucleus on BT483 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded BT483 xenograft. PAX8 antibody (TA308698) dilution: 1:500.
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Immunofluorescence analysis of paraformaldehyde-fixed A549, using PAX8(TA308698) antibody at 1:200 dilution.
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PAX8 antibody immunoprecipitates PAX8 protein in IP experiments. IP Sample: 1000 ug 293T whole cell lysate/extract A. 40 ug 293T whole cell lysate/extract B. Control with 2 ug of preimmune rabbit IgG C. Immunoprecipitation of PAX8 protein by 2 ug of PAX8
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