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Home Antibody All anti-STK4 antibodies

Anti-STK4 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308695
  • Rabbit Polyclonal antibody to STK4 (serine/threonine kinase 4)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401893) , 20ug Explanation
100ul 325 3-7 Days
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WB(2)
IP(1)
IHC(1)
IF(1)
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Also for STK4 (NM_006282)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 324 and 418 of STK4 (Uniprot ID#Q13043)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Rat, Chicken, Rhesus Monkey, Bovine) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF, IP Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 56kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rat (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%)

Reference Data

Target NameHomo sapiens serine/threonine kinase 4 (STK4)
Alternative NameKRS2; MST1; TIIAC; YSK3
Database LinkNP_006273
Entrez Gene 6789 Human
Entrez Gene 58231 Mouse
Entrez Gene 311622 Rat
Entrez Gene 717730 Monkey
FunctionThe protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq]
Related PathwayProtein KinaseDruggable Genome MAPK signaling pathwayPathways in cancerNon-small cell lung cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (50 ug of whole cell lysate). A: Mouse brain. 7.5% SDS PAGE. TA308695 diluted at 1:2000.
WB Image
Sample (30 ug of whole cell lysate). A: Hep G2 . 7.5% SDS PAGE. STK4 antibody. TA308695 diluted at 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using MST1(TA308695) antibody at 1:500 dilution.
IF Image
Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed U2OS, using STK4(TA308695) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:2000.
IP Image
STK4 antibody immunoprecipitates STK4 protein in IP experiments. IP samples: HepG2 whole cell extract. A. 50 ug HepG2 whole cell extract. B. Control with 4 ug of preimmune Rabbit IgG. C. Immunoprecipitation of STK4 protein by 4 ug STK4 antibody (TA308695)

 

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