Home Antibody All anti-SDHB antibodies
Also for SDHB (NM_003000)
|Synthetic peptide contain a sequence corresponding to a region within amino acids 271 and 280 of SDHB|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (SDHB)|
|CWS2; IP; PGL4; SDH; SDH1; SDH2; SDHIP|
|Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq]|
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Sample(30 ug of whole cell lysate) A:MOLT4 (anti-SDHB antibody diluted at 1:1000)
Immunofluorescence analysis of methanol-fixed HeLa, using SDHB(anti-SDHB antibody) antibody at 1:200 dilution.