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Home Antibody All anti-SDHB antibodies

Anti-SDHB Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308686
  • Rabbit Polyclonal antibody to SDHB (succinate dehydrogenase complex, subunit B, iron sulfur (Ip))
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401052) , 20ug
100ul 325 In Stock
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WB(1)
IF(1)
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Also for SDHB (NM_003000)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide contain a sequence corresponding to a region within amino acids 271 and 280 of SDHB
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB:1:500-1:3000; IF:1:100-1:200;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (SDHB)
Alternative NameCWS2; IP; PGL4; SDH; SDH1; SDH2; SDHIP
Database LinkNP_002991
FunctionComplex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq]
Related Pathway

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WB Image
Sample(30 ug of whole cell lysate) A:MOLT4 (anti-SDHB antibody diluted at 1:1000)
IF Image
Immunofluorescence analysis of methanol-fixed HeLa, using SDHB(anti-SDHB antibody) antibody at 1:200 dilution.

 

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