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Anti-PFKM Antibody

WB(1)

Gene Name Homo sapiens phosphofructokinase, muscle (PFKM), transcript variant 4 Synonyms: GSD7; PFK-1; PFK1; PFKA; PFKX Immunogen Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 223 of Human PFKM Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Clone Name Isotype IgG Species Reactivity Human, Mouse Concentration 0.92mg/ml Purification Purified by antigen-affinity chromatography. (Protein A or G Sepharose) Guaranteed Application * WB Suggested Dilutions WB:1:1000-1:10000; Background The PFKM gene encodes the muscle isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. Mammalian PFK is a tetramer made up of various combinations of 3 subunits: muscle (PFKM), liver (PFKL; MIM 171860), and platelet (PFKP; MIM 171840), the genes for which are located on chromosomes 12q13, 21q22, and 10p, respectively. The composition of the tetramers differs according to the tissue type. Muscle and liver PFK are a homotetramers of 4M and 4L subunits, respectively. Erythrocytes contain both L and M subunits, which randomly tetramerize to form M4, L4, and M3L, M2L2, and ML3 hybrid forms of the holoenzyme (Vora et al., 1980 [PubMed 6444721]; Raben and Sherman, 1995 [PubMed 7550225]).[supplied by OMIM] Related Pathway

Related Lysate from OriGene • Transient overexpression lysate of phosphofructokinase, muscle (PFKM), transcript variant 4 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • PFKM - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • PFKM - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Pfkm - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • PFKM - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Pfkm - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens phosphofructokinase, muscle (PFKM), transcript variant 4 as transfection-ready DNA • Lenti ORF clone of Human phosphofructokinase, muscle (PFKM), transcript variant 4, mGFP tagged • GFP-tagged ORF clone of Homo sapiens phosphofructokinase, muscle (PFKM), transcript variant 4 as transfection-ready DNA • Lenti ORF clone of Human phosphofructokinase, muscle (PFKM), transcript variant 4 , Myc-DDK-tagged • Myc-DDK-tagged ORF clone of Homo sapiens phosphofructokinase, muscle (PFKM), transcript variant 4 as 200 ug transfection-ready DNA Related cDNA Clones • Homo sapiens phosphofructokinase, muscle (PFKM), transcript variant 4 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)