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Home Antibody All anti-NKX2-5 antibodies

Anti-NKX2-5 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308654
  • Rabbit Polyclonal antibody to Nkx2.5 (NK2 transcription factor related, locus 5 (Drosophila))
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401397) , 20ug
100ul 325 3-7 Days
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WB(1)
IF(2)
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Also for NKX2-5 (NM_004387)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 188 of NKX2-5
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB:1:500-1:3000; IF:1:100-1:500;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens NK2 homeobox 5 (NKX2-5), transcript variant 1
Alternative NameCHNG5; CSX; CSX1; HLHS2; NKX2.5; NKX2E; NKX4-1; VSD3
Database LinkNP_004378
FunctionHomeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]). It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.[supplied by OMIM]
Related Pathway

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WB Image
Sample(30 ug whole cell lysate) A:H1299 B:Raji (anti-NKX2-5 antibody diluted at 1:1000)
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NKX2-5(anti-NKX2-5 antibody) antibody at 1:200 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed mouse ESC D3, using Nkx2.5(anti-NKX2-5 antibody) antibody at 1:200 dilution.

 

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