Home Antibody All anti-NKX2-5 antibodies
Also for NKX2-5 (NM_004387)
|Recombinant fragment corresponding to a region within amino acids 1 and 218 of Nkx2.5 (Uniprot ID#P52952)|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens NK2 homeobox 5 (NKX2-5), transcript variant 1|
|CHNG5; CSX; CSX1; HLHS2; NKX2.5; NKX2E; NKX4-1; VSD3|
Entrez Gene 1482 Human
Entrez Gene 18091 Mouse
|Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]). It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.[supplied by OMIM]|
|Transcription Factors |
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Sample(30 ug whole cell lysate). A:H1299. B:Raji . 10% SDS PAGE. TA308654 diluted at 1:1000
Sample (50 ug of whole cell lysate). A: mouse heart. 10% SDS PAGE. TA308654 diluted at 1:1000.
Nkx2.5 antibody detects NKX2-5 protein by Western blot analysis. A. 50 ug rat heart lysate/extract. 10 % SDS-PAGE. Nkx2.5 antibody (TA308654) dilution: 1:500
Immunofluorescence analysis of paraformaldehyde-fixed mouse ESC D3, using Nkx2.5(TA308654) antibody at 1:200 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NKX2-5(TA308654) antibody at 1:200 dilution.