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Home Antibody All anti-ATRX antibodies

Anti-ATRX Antibody

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SKU Description Amount Price Availability*  
TA308651
  • Rabbit Polyclonal antibody to Rad54 (alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae))
100ul $325 In Stock
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 2161 and 2413 of ATRX
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB:1:500-1:3000; IHC:1:100; IF:1:100-1:200;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens alpha thalassemia/mental retardation syndrome X-linked (ATRX), transcript variant 1
Alternative NameATR2; JMS; MRXHF1; RAD54; RAD54L; SFM1; SHS; XH2; XNP; ZNF-HX
Database LinkNP_000480
FunctionThe protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
Related Pathway

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WB Image
Sample (30ug whole cell lysate) A:293T B:HepG2 C:Raji (anti-ATRX antibody diluted at 1:500)
IHC Image
Immunohistochemical analysis of paraffin-embedded A549 xenograft, using ATRX(anti-ATRX antibody) antibody at 1:100 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using ATRX(anti-ATRX antibody) antibody at 1:200 dilution.

 

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