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Home Antibody All anti-IL24 antibodies

Anti-IL24 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308643
  • Rabbit polyclonal antibody to Interleukin-24 (interleukin 24)
100ul 325 In Stock
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WB(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 142 and 206 of IL24 (Uniprot ID#Q13007)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat) Concentration0.46mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 24kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (93%), Rat (80%)

Reference Data

Target NameHomo sapiens interleukin 24 (IL24), transcript variant 2
Alternative NameC49A; FISP; IL-24; IL10B; mda-7; MDA7; Mob-5; ST16
Database LinkNP_851936
Entrez Gene 11009 Human
Entrez Gene 93672 Mouse
Entrez Gene 170819 Rat
FunctionThis gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
Related PathwaySecreted ProteinDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathway

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WB Image
Sample (30 ug of whole cell lysate). A: A431 . 12% SDS PAGE. TA308643 diluted at 1:1000.

 

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