Home Antibody All anti-IL24 antibodies
Also for IL24 (NM_181339)
|Synthetic peptide corresponding to a region within amino acids 142 and 206 of IL24 (Uniprot ID#Q13007)|
|Human (Predicted: Mouse, Rat)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (93%), Rat (80%)
|Homo sapiens interleukin 24 (IL24), transcript variant 2|
|C49A; FISP; IL-24; IL10B; mda-7; MDA7; Mob-5; ST16|
Entrez Gene 11009 Human
Entrez Gene 93672 Mouse
Entrez Gene 170819 Rat
|This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]|
|Secreted ProteinDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathway|
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Sample (30 ug of whole cell lysate). A: A431 . 12% SDS PAGE. TA308643 diluted at 1:1000.