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Home Antibody All anti-PFKL antibodies

Anti-PFKL Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308631
  • Rabbit Polyclonal antibody to PFKL (phosphofructokinase, liver)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424324) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for PFKL (NM_001002021)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 428 and 674 of PFKL (Uniprot ID#P17858)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Bovine) Concentration0.8mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 90kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (95%), Rat (95%), Bovine (94%)

Reference Data

Target NameHomo sapiens phosphofructokinase, liver (PFKL), transcript variant 1
Alternative NameATP-PFK; PFK-B; PFK-L
Database LinkNP_001002021
Entrez Gene 5211 Human
Entrez Gene 18641 Mouse
Entrez Gene 25741 Rat
FunctionPhosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. Separate genes encode a muscle subunit (M) and a liver subunit (L). PFK from muscle is a homotetramer of M subunits, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits. The protein encoded by this gene represents the L subunit. Alternate splicing results in two transcript variants, one of which is a candidate for nonsense-mediated decay (NMD). [provided by RefSeq]
Related PathwayDruggable Genome Glycolysis / GluconeogenesisPentose phosphate pathwayFructose and mannose metabolismGalactose metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: Hep G2 . 7.5% SDS PAGE. TA308631 diluted at 1:1000
IHC Image
Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using PFKL(TA308631) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed A549, using PFKL(TA308631) antibody at 1:200 dilution.

 

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