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Anti-PSAP Antibody


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SKU Description Amount Price Availability*  
TA308630 Rabbit polyclonal antibody to PSAP (prosaposin) 100ul $325 3-7 Days
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 250 of PSAP (Uniprot ID#P07602)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Pig) Concentration0.97mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 58kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Pig (87%)

Reference Data

Target NameHomo sapiens prosaposin (PSAP), transcript variant 2
Alternative NameGLBA; SAP1
Database LinkNP_001035930
Entrez Gene 5660 Human
FunctionThis gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
Related PathwayDruggable Genome Lysosome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: Molt-4 . 7.5% SDS PAGE. TA308630 diluted at 1:2000.

IHC Image
Immunohistochemical analysis of paraffin-embedded NCIN87 xenograft , using PSAP(TA308630) antibody at 1:500 dilution.


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