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Home Antibody All anti-HOMER3 antibodies

Anti-HOMER3 Antibody

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SKU Description Amount Price Availability*  
TA308627
  • Rabbit polyclonal antibody to Homer-3 (homer homolog 3 (Drosophila))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC428987) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(1)
IF(1)
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Also for HOMER3 (NM_001145724)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 55 and 305 of Homer3 (Uniprot ID#Q9NSC5)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 40kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (85%), Rat (86%)

Reference Data

Target NameHomo sapiens homer homolog 3 (Drosophila) (HOMER3), transcript variant 4
Alternative NameHOMER-3; VESL3
Database LinkNP_001139196
Entrez Gene 9454 Human
Entrez Gene 26558 Mouse
Entrez Gene 29548 Rat
FunctionThis gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: NT2D1. 10% SDS PAGE. TA308627 diluted at 1:1000.
IHC Image
Homer3 antibody detects Homer3 protein at cytoplasm on Papillary adenocarcinoma by immunohistochemical analysis. Sample: Paraffin-embedded Papillary adenocarcinoma . Homer3 antibody (TA308627) dilution: 1:250.
IF Image
Immunofluorescence analysis of methanol-fixed HeLa, using Homer3(TA308627) antibody at 1:500 dilution.

 

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