Home Antibody All anti-HOMER3 antibodies
Also for HOMER3 (NM_001145724)
|Recombinant fragment corresponding to a region within amino acids 55 and 305 of Homer3 (Uniprot ID#Q9NSC5)|
|Human (Predicted: Mouse, Rat)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (85%), Rat (86%)
|Homo sapiens homer scaffolding protein 3 (HOMER3), transcript variant 4|
Entrez Gene 9454 Human
Entrez Gene 26558 Mouse
Entrez Gene 29548 Rat
|This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.|
|Druggable Genome |
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Sample (30 ug of whole cell lysate). A: NT2D1. 10% SDS PAGE. TA308627 diluted at 1:1000.
Homer3 antibody detects Homer3 protein at cytoplasm on Papillary adenocarcinoma by immunohistochemical analysis. Sample: Paraffin-embedded Papillary adenocarcinoma . Homer3 antibody (TA308627) dilution: 1:250.
Immunofluorescence analysis of methanol-fixed HeLa, using Homer3(TA308627) antibody at 1:500 dilution.