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Home Antibody All anti-UBE4B antibodies

Anti-UBE4B Antibody

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SKU Description Amount Price Availability*  
TA308624 Rabbit polyclonal antibody to UBE4B (ubiquitination factor E4B (UFD2 homolog, yeast)) 100ul $325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 869 and 1179 of UBE4B (Uniprot ID#O95155)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Bovine) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:5000-1:20000
Predicted MW Explanation 133kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Bovine (100%)

Reference Data

Target NameHomo sapiens ubiquitination factor E4B (UBE4B), transcript variant 1
Alternative NameE4; HDNB1; UBOX3; UFD2; UFD2A
Database LinkNP_001099032
Entrez Gene 10277 Human
FunctionThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]
Related Pathway Ubiquitin mediated proteolysis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: Hep G2 . 5% SDS PAGE. TA308624 diluted at 1:10000
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Immunohistochemical analysis of paraffin-embedded CA922 xenograft, using UBE4B(TA308624) antibody at 1:500 dilution.
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Immunofluorescence analysis of methanol-fixed Hep3B, using UBE4B(TA308624) antibody at 1:500 dilution.
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