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Home Antibody All anti-GRAP antibodies

Anti-GRAP Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308618 Rabbit Polyclonal antibody to GRAP (GRB2-related adaptor protein) 100ul $325 3-7 Days
LC416529 GRAP HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 155 and 217 of GRAP (Uniprot ID#Q13588)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Rhesus Monkey, Bovine) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 25kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (92%)

Reference Data

Target NameHomo sapiens GRB2-related adaptor protein (GRAP)
Alternative NameMGC64880
Database LinkNP_006604
Entrez Gene 10750 Human
Entrez Gene 71520 Mouse
Entrez Gene 363616 Rat
Entrez Gene 702473 Monkey
FunctionThis gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. [provided by RefSeq]
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: A549 12% SDS PAGE. TA308618 diluted at 1:1000.
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Immunohistochemical analysis of paraffin-embedded U373 xenograft, using GRAP(TA308618) antibody at 1:100 dilution.
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Immunofluorescence analysis of methanol-fixed A549, using GRAP(TA308618) antibody at 1:500 dilution.
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