Home Antibody All anti-FUT3 antibodies
Also for FUT3 (NM_001097641)
|Recombinant fragment corresponding to a region within amino acids 98 and 315 of Blood Group Lewis a (Uniprot ID#P21217)|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (FUT3), transcript variant 4|
|CD174; FT3B; FucT-III; LE; Les|
Entrez Gene 2525 Human
|The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq]|
| Glycosphingolipid biosynthesis - lacto and neolacto seriesMetabolic pathways|
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Sample (30 ug of whole cell lysate). A: Molt-4 . 10% SDS PAGE. TA308602 diluted at 1:1000.