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Home Antibody All anti-FUT3 antibodies

Anti-FUT3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308602
  • Rabbit polyclonal antibody to FUT3 (fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group))
100ul 325 3-7 Days
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WB(1)
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Also for FUT3 (NM_001097641)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 98 and 315 of Blood Group Lewis a (Uniprot ID#P21217)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 42kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (FUT3), transcript variant 4
Alternative NameCD174; FT3B; FucT-III; LE; Les
Database LinkNP_001091110
Entrez Gene 2525 Human
FunctionThe Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq]
Related Pathway Glycosphingolipid biosynthesis - lacto and neolacto seriesMetabolic pathways

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WB Image
Sample (30 ug of whole cell lysate). A: Molt-4 . 10% SDS PAGE. TA308602 diluted at 1:1000.

 

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