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Home Antibody All anti-BMPR2 antibodies

Anti-BMPR2 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308587 Rabbit polyclonal antibody to BMPR2 (bone morphogenetic protein receptor, type II (serine/threonine kinase)) 100ul $325 In Stock
LC420077 BMPR2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for BMPR2 (NM_001204)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 667 and 951 of BMPR2 (Uniprot ID#Q13873)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Pig) Concentration0.89mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 115kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Pig (92%)

Reference Data

Target NameHomo sapiens bone morphogenetic protein receptor, type II (serine/threonine kinase) (BMPR2)
Alternative NameBMPR-II; BMPR3; BMR2; BRK-3; POVD1; PPH1; T-ALK
Database LinkNP_001195
Entrez Gene 659 Human
Entrez Gene 12168 Mouse
FunctionThis gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq]
Related PathwayProtein KinaseTransmembraneDruggable Genome Cytokine-cytokine receptor interactionTGF-beta signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug of whole cell lysate). A:H1299. B:Raji . 7.5% SDS PAGE. TA308587 diluted at 1:1000

WB Image
Sample (30 ug of whole cell lysate). . A:NIH-3T3. 7.5% SDS PAGE. . TA308587 diluted at 1:1000.


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