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Home Antibody All anti-WT1 antibodies

Anti-WT1 Antibody

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SKU Description Amount Price Availability*  
TA308577
  • Rabbit polyclonal antibody to WT1 (Wilms tumor 1)
100ul 325 In Stock
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WB(1)
IF(1)

OriGene Data

Immunogen277 - 505 of Human WT1
Clone Name IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB:1:500-1:3000; IHC:1:100-1:1000; IF:1:100-1:1000;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens Wilms tumor 1 (WT1), transcript variant C
Alternative NameAWT1; GUD; WAGR; WIT-2; WT33;GUD; WAGR; WIT-2; WT33; Wilms tumor 1
Database LinkNP_077743
FunctionThis gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq]
Related Pathway

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WB Image
A: Molt-4 B: Raji (anti-WT1 antibody diluted at 1:1000)
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using WT1(anti-WT1 antibody) antibody at 1:200 dilution.

 

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