OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-BCCIP antibodies

Anti-BCCIP Antibody

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308557
  • Rabbit polyclonal antibody to TOK-1 alpha (BRCA2 and CDKN1A interacting protein)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC413842) , 20ug
100ul 325 3-7 Days
Add to Shopping Cart
WB(1)
IF(1)

OriGene Data

Immunogen181 - 243 of Human BCCIP
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB:1:1000; IF:1:200
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant A
Alternative NameTOK-1; TOK1
Database LinkNP_057651
FunctionThis gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
A: A431 B: Hela (anti-BCCIP antibody diluted at 1:1000)
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using TOK-1 alpha (anti-BCCIP antibody) antibody at 1:200 dilution.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title