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Home Antibody All anti-IL1R2 antibodies

Anti-IL1R2 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308544 Rabbit Polyclonal antibody to IL1 receptor 2 (interleukin 1 receptor, type II) 100ul $325 3-7 Days
LC406630 IL1R2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for IL1R2 (NM_173343)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 172 and 398 of IL1 Receptor 2 (Uniprot ID#P27930)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Monkey) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 45kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Monkey (94%)

Reference Data

Target NameHomo sapiens interleukin 1 receptor, type II (IL1R2), transcript variant 2
Alternative NameCD121b; IL1RB; MGC47725
Database LinkNP_775465
Entrez Gene 7850 Human
Entrez Gene 711638 Monkey
FunctionThe protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq]
Related PathwayTransmembraneDruggable Genome MAPK signaling pathwayCytokine-cytokine receptor interactionHematopoietic cell lineage

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: 293T. 10% SDS PAGE. TA308544 diluted at 1:1000
Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using IL1R2(TA308544) antibody at 1:100 dilution.
Immunofluorescence analysis of methanol-fixed A549, using IL1 Receptor 2(TA308544) antibody at 1:500 dilution.


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