Home Antibody All anti-KLC1 antibodies
Also for KLC1 (NM_182923)
|Recombinant fragment corresponding to a region within amino acids 114 and 441 of KLC1 (Uniprot ID#Q07866)|
|Human (Predicted: Mouse, Rat, Bovine)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (97%), Rat (98%), Bovine (99%)
|Homo sapiens kinesin light chain 1 (KLC1), transcript variant 2|
|KLC; KNS2; KNS2A|
Entrez Gene 3831 Human
Entrez Gene 16593 Mouse
Entrez Gene 171041 Rat
|Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined. [provided by RefSeq]|
|Druggable Genome |
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Sample (30 ug of whole cell lysate). A: A549. 7.5% SDS PAGE. TA308531 diluted at 1:1000.