Home Antibody All anti-MCM7 antibodies
Also for MCM7 (NM_182776)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 14 and 275 of MCM7|
||0.5~1.0 mg/ml (Lot Dependent)
|WB, IHC, IF
||WB:1:500-1:3000; IHC:1:100; IF:1:100-1:200;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens minichromosome maintenance complex component 7 (MCM7), transcript variant 2|
|CDC47; MCM2; P1.1-MCM3; P1CDC47; P85MCM; PNAS146|
|The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]|
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Sample (30 ug of whole cell lysate) A: H1299 (anti-MCM7 antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded Cal27 Xenograft, using MCM7(anti-MCM7 antibody) antibody at 1:100 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using MCM7(anti-MCM7 antibody) antibody at 1:200 dilution.