Home Antibody All anti-UBE2B antibodies
Also for UBE2B (NM_003337)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 122 of UBE2B|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens ubiquitin-conjugating enzyme E2B (UBE2B)|
|E2-17kDa; HHR6B; HR6B; RAD6B; UBC2|
Entrez Gene 7320 Human
Entrez Gene 22210 Mouse
|The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq]|
|Druggable Genome Ubiquitin mediated proteolysis|
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A: Hela ( UBE2B antibody anti-UBE2B antibody diluted at 1:1000)
A: NIH-3T3(anti-UBE2B antibody diluted at 1:1000)