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Also for HRAS (NM_176795)
|Synthetic peptide corresponding to a region within amino acids 111 and 189 of H-Ras (Uniprot ID#P01112)|
|Human (Predicted: Xenopus laevis, Xenopus Tropicalis, Chicken, Rhesus Monkey, Bovine)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Xenopus laevis (100%), Xenopus Tropicalis (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (88%)
|Homo sapiens Harvey rat sarcoma viral oncogene homolog (HRAS), transcript variant 2|
|C-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; H-RASIDX; HAMSV; HRAS1; p21ras; RASH1|
Entrez Gene 3265 Human
Entrez Gene 698830 Monkey
|This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq]|
|Druggable Genome MAPK signaling pathwayErbB signaling pathwayChemokine signaling pathwayEndocytosisAxon guidanceVEGF signaling pathwayMore Pathways >> |
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H-Ras antibody detects HRAS protein by Western blot analysis. A. 30 ug PC-12 whole cell lysate/extract. B. 30 ug Rat2 whole cell lysate/extract. 12 % SDS-PAGE. H-Ras antibody (TA308498) dilution: 1:1000
Sample (30 ug of whole cell lysate). A: Hela. B: Hep G2 . C: Molt-4 . 12% SDS PAGE. TA308498 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded OVCAR3 xenograft , using H-Ras (TA308498) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using H-Ras (TA308498) antibody at 1:200 dilution.