Home Antibody All anti-LBP antibodies
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 166 and 437 of Human LBP|
||0.5~1.0 mg/ml (Lot Dependent)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens lipopolysaccharide binding protein (LBP)|
|The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Finally, this gene is found on chromosome 20, immediately downstream of the BPI gene. [provided by RefSeq]|
Toll-like receptor signaling pathway
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Sample(30 ug whole cell lysate) A:H1299 (anti-LBP antibody diluted at 1:500)
Immunohistochemical analysis of paraffin-embedded Gastric N+T, using LBP(anti-LBP antibody) antibody at 1:100 dilution.