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Also for FPGT (NM_003838)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 146 and 423 of Human FPGT|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens fucose-1-phosphate guanylyltransferase (FPGT), transcript variant 1|
|L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. [provided by RefSeq]|
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Sample(30 ug of whole cell lysate) A:Raji (anti-FPGT antibody diluted at 1:500)
Immunohistochemical analysis of paraffin-embedded MDA-MB-468 xenograft, using FPGT(anti-FPGT antibody) antibody at 1:100 dilution.