Home Antibody All anti-SSRP1 antibodies
Also for SSRP1 (NM_003146)
|Recombinant fragment corresponding to a region within amino acids 75 and 338 of SSRP1 (Uniprot ID#Q08945)|
|Human (Predicted: Mouse, Rat, Rhesus Monkey, Bovine)
||Lot dependent; please refer to CoA along with shipment
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (100%)
|Homo sapiens structure specific recognition protein 1 (SSRP1)|
|FACT; FACT80; T160|
Entrez Gene 6749 Human
Entrez Gene 20833 Mouse
Entrez Gene 81785 Rat
Entrez Gene 706614 Monkey
|The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq]|
|Transcription Factors |
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Sample (30 ug of whole cell lysate). A: Molt-4 . 7.5% SDS PAGE. TA308461 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded Cal27 Xenograft, using SSRP1(TA308461) antibody at 1:100 dilution.