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Home Antibody All anti-SSRP1 antibodies

Anti-SSRP1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308461
  • Rabbit polyclonal antibody to SSRP1 (structure specific recognition protein 1)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC418869) , 20ug
100ul $325 Next Day
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WB(1)
IHC(1)
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Also for SSRP1 (NM_003146)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 75 and 308 of SSRP1
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB:1:500-1:3000; IHC:1:100;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens structure specific recognition protein 1 (SSRP1)
Alternative NameFACT; FACT80; T160
Database LinkNP_003137
FunctionThe protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq]
Related Pathway

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WB Image
Sample (30 ug of whole cell lysate) A: Molt-4 (anti-SSRP1 antibody diluted at 1:1000)
IHC Image
Immunohistochemical analysis of paraffin-embedded Cal27 Xenograft, using SSRP1(anti-SSRP1 antibody) antibody at 1:100 dilution.

 

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