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Home Antibody All anti-SSRP1 antibodies

Anti-SSRP1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308461 Rabbit polyclonal antibody to SSRP1 (structure specific recognition protein 1) 100ul $325 In Stock
LC418869 SSRP1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for SSRP1 (NM_003146)
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 75 and 338 of SSRP1 (Uniprot ID#Q08945)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Rhesus Monkey, Bovine) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 81kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (100%)

Reference Data

Target NameHomo sapiens structure specific recognition protein 1 (SSRP1)
Alternative NameFACT; FACT80; T160
Database LinkNP_003137
Entrez Gene 6749 Human
Entrez Gene 20833 Mouse
Entrez Gene 81785 Rat
Entrez Gene 706614 Monkey
FunctionThe protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq]
Related PathwayTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: Molt-4 . 7.5% SDS PAGE. TA308461 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded Cal27 Xenograft, using SSRP1(TA308461) antibody at 1:100 dilution.


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