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Home Antibody All anti-TRADD antibodies

Anti-TRADD Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308445
  • Rabbit Polyclonal antibody to TRADD (TNFRSF1A-associated via death domain)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401247) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 1 and 43 of TRADD (Uniprot ID#Q15628)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat) Concentration0.54mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 34kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (100%), Rat (92%)

Reference Data

Target NameHomo sapiens TNFRSF1A-associated via death domain (TRADD)
Alternative NameHs.89862
Database LinkNP_003780
Entrez Gene 8717 Human
Entrez Gene 71609 Mouse
Entrez Gene 246756 Rat
FunctionThe protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq]
Related PathwayDruggable Genome ApoptosisRIG-I-like receptor signaling pathwayAdipocytokine signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (10 ug of whole cell lysate). A: A549. B: SiHa. 10% SDS PAGE. TA308445 diluted at 1:1000.
IHC Image
TRADD antibody [N1], N-term detects TRADD protein at cytosol on colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded colon carcinoma. TRADD antibody [N1], N-term (TA308445) dilution: 1:500.
IF Image
Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using TRADD(TA308445) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:2000.

 

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