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Anti-P4HB Antibody

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IHC(1)

IF(1)

OriGene Data

Immunogen	Recombinant protein fragment contain a sequence corresponding to a region within amino acids 23 and 197 of Human P4HB
Clone Name		Isotype	IgG
Species Reactivity	Human, Mouse	Concentration	1mg/ml
Guaranteed Application *	WB, IHC, IF	Suggested Dilutions	WB:1:500-1:10000; IHC:1:100; IF:1:100-1:500;
Buffer	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification	Purified by antigen-affinity chromatography. (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens prolyl 4-hydroxylase, beta polypeptide (P4HB)
Alternative Name	DSI; ERBA2L; GIT; P4Hbeta; PDI; PDIA1; PHDB; PO4DB; PO4HB; PROHB
Database Link	NP_000909
Function	This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq]
Related Pathway

Related Lysate from OriGene • Transient overexpression lysate of prolyl 4-hydroxylase, beta polypeptide (P4HB) Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • P4HB - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • P4HB - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • P4hb - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • P4HB - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • P4hb - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens prolyl 4-hydroxylase, beta polypeptide (P4HB) as transfection-ready DNA • Lenti ORF clone of Human prolyl 4-hydroxylase, beta polypeptide (P4HB), mGFP tagged • Lenti ORF clone of Human prolyl 4-hydroxylase, beta polypeptide (P4HB) , Myc-DDK-tagged • GFP-tagged ORF clone of Homo sapiens prolyl 4-hydroxylase, beta polypeptide (P4HB) as transfection-ready DNA Related cDNA Clones • Homo sapiens prolyl 4-hydroxylase, beta polypeptide (P4HB) as transfection-ready DNA • Homo sapiens prolyl 4-hydroxylase, beta polypeptide (P4HB) as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)