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Home Antibody All anti-P4HB antibodies

Anti-P4HB Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308403
  • Rabbit Polyclonal antibody to PDI (prolyl 4-hydroxylase, beta polypeptide)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400335) , 20ug
100ul 325 In Stock
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WB(1)
IHC(1)
IF(1)
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Also for P4HB (NM_000918)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 23 and 197 of Human P4HB
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB:1:500-1:10000; IHC:1:100; IF:1:100-1:500;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens prolyl 4-hydroxylase, beta polypeptide (P4HB)
Alternative NameDSI; ERBA2L; GIT; P4Hbeta; PDI; PDIA1; PHDB; PO4DB; PO4HB; PROHB
Database LinkNP_000909
FunctionThis gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq]
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug of whole cell lysate) A:293T B:A431 C:H1299 (anti-P4HB antibody diluted at 1:500)
IHC Image
Immunohistochemical analysis of paraffin-embedded H520 xenograft, using PDI(anti-P4HB antibody) antibody at 1:100 dilution.
IF Image
Immunofluorescence analysis of methanol-fixed A431, using PDI(anti-P4HB antibody) antibody at 1:200 dilution.

 

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