Home Antibody All anti-RGS14 antibodies
Also for RGS14 (NM_006480)
|Synthetic peptide contain a sequence corresponding to a region within amino acids 504 and 566 of Human RGS14|
||0.5~1.0 mg/ml (Lot Dependent)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens regulator of G-protein signaling 14 (RGS14)|
|regulator of G-protein signalling 14; regulator of G-protein signaling 14|
|This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]|
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Sample (30ug whole cell lysate) A:MOLT4 (anti-RGS14 antibody diluted at 1:500)
Immunohistochemical analysis of paraffin-embedded GASTRIC CA, using RGS14(anti-RGS14 antibody) antibody at 1:100 dilution.