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Home Antibody All anti-RGS14 antibodies

Anti-RGS14 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308383
  • Rabbit Polyclonal antibody to RGS14 (regulator of G-protein signaling 14)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416615) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for RGS14 (NM_006480)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 504 and 566 of RGS14 (Uniprot ID#O43566)
Clone Name IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 61kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens regulator of G-protein signaling 14 (RGS14)
Alternative Nameregulator of G-protein signalling 14; regulator of G-protein signaling 14
Database LinkNP_006471
Entrez Gene 10636 Human
FunctionThis gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
RGS14 antibody [C3], C-term detects RGS14 protein by Western blot analysis. A. 30 ug Jurkat whole lysate/extract. 7.5 % SDS-PAGE. RGS14 antibody [C3], C-term (TA308383) dilution: 1:500
IHC Image
Immunohistochemical analysis of paraffin-embedded GASTRIC CA, using RGS14(TA308383) antibody at 1:100 dilution.

 

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