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Home Antibody All anti-LITAF antibodies

Anti-LITAF Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308382 Rabbit polyclonal antibody to LITAF (lipopolysaccharide-induced TNF factor) 100ul $325 3-7 Days
LC427884 LITAF HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 161 of LITAF (Uniprot ID#Q99732)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Bovine) Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 17kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (85%), Rat (86%), Bovine (86%)

Reference Data

Target NameHomo sapiens lipopolysaccharide-induced TNF factor (LITAF), transcript variant 3
Alternative NamePIG7; SIMPLE; TP53I7
Database LinkNP_001129945
Entrez Gene 9516 Human
Entrez Gene 56722 Mouse
Entrez Gene 65161 Rat
FunctionLipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: Hep G2 . 12% SDS PAGE. TA308382 diluted at 1:1000

IHC Image
LITAF antibody [N1C3] detects LITAF protein at cytoplasm on placenta by immunohistochemical analysis. Sample: Paraffin-embedded placenta. LITAF antibody [N1C3] (TA308382) dilution: 1:100.


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