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Also for LITAF (NM_001136473)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 132 of Human LITAF|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens lipopolysaccharide-induced TNF factor (LITAF), transcript variant 3|
|PIG7; SIMPLE; TP53I7|
|Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]|
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Sample (30 ug of whole cell lysate) A: HepG2 (anti-LITAF antibody diluted at 1:1000)