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Also for GAD2 (NM_001134366)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 353 and 556 of GAD65|
||0.5~1.0 mg/ml (Lot Dependent)
||WB:1:500-1:3000; IHC:1:100; IF:1:100-1:500;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) (GAD2), transcript variant 2|
|This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq]|
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Immunohistochemical analysis of paraffin-embedded OECM1 xenograft, using GAD65(anti-GAD2 antibody) antibody at 1:100 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using GAD65(anti-GAD2 antibody) antibody at 1:200 dilution.