Home Antibody All anti-GRAP2 antibodies
Also for GRAP2 (NM_004810)
|Recombinant fragment corresponding to a region within amino acids 1 and 174 of GRAP2 (Uniprot ID#O75791)|
|Human (Predicted: Mouse, Rat, Bovine)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (90%), Rat (92%), Bovine (90%)
|Homo sapiens GRB2-related adaptor protein 2 (GRAP2), transcript variant 3|
|GADS; GRAP-2; GRB2L; GRBLG; GrbX; Grf40; GRID; GRPL; Mona; P38|
Entrez Gene 9402 Human
Entrez Gene 17444 Mouse
Entrez Gene 366962 Rat
|This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq]|
|Druggable Genome T cell receptor signaling pathway|
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Sample (30 ug of whole cell lysate). A: JurKat. 10% SDS PAGE. TA308365 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded Colon ca, using GRAP2(TA308365) antibody at 1:500 dilution.