Home Antibody All anti-AP2M1 antibodies
Also for AP2M1 (NM_001025205)
|Recombinant fragment contain a sequence corresponding to a region within amino acids 1 and 150 of AP2M1 (Uniprot ID#Q96CW1)|
|Human (Predicted: Mouse, Rat, Bovine)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (100%), Rat (100%), Bovine (100%)
|Homo sapiens adaptor-related protein complex 2, mu 1 subunit (AP2M1), transcript variant 2|
|AP50; CLAPM1; mu2|
Entrez Gene 1173 Human
Entrez Gene 11773 Mouse
Entrez Gene 116563 Rat
|This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Druggable Genome EndocytosisHuntington's disease|
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Sample(30 ug of whole cell lysate). A:293T. B:HeLa S3. 10% SDS PAGE. TA308343 diluted at 1:500
Immunohistochemical analysis of paraffin-embedded N87 xenograft, using AP2M1(TA308343) antibody at 1:100 dilution.