Home Antibody All anti-ATXN3 antibodies
Also for ATXN3 (NM_001127697)
|Recombinant fragment corresponding to a region within amino acids 1 and 245 of Ataxin 3 (Uniprot ID#P54252)|
|Human, Mouse (Predicted: Pig, Rat, Bovine)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Pig (99%), Rat (96%), Bovine (98%)
|Homo sapiens ataxin 3 (ATXN3), transcript variant e|
|AT3; ATX3; JOS; MJD; MJD1; SCA3|
Entrez Gene 4287 Human
Entrez Gene 110616 Mouse
Entrez Gene 60331 Rat
|Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is the cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]|
|Transcription FactorsDruggable Genome |
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Ataxin 3 antibody detects Ataxin 3 protein by western blot analysis. Mouse tissue extracts (50 ug) was separated by 10 % SDS-PAGE, and blotted with Ataxin 3 antibody (TA308320) diluted by 1:500
Ataxin 3 antibody detects Ataxin 3 protein by western blot analysis. 293T mock transfected (-) or transfected with a construct expressing human Ataxin 3 (+). 10 % SDS-PAGE. Ataxin 3 antibody (TA308320) dilution: 1:5000
Immunohistochemical analysis of paraffin-embedded H661 xenograft, using Ataxin 3(TA308320) antibody at 1:500 dilution.