Home Antibody All anti-ATXN3 antibodies
Also for ATXN3 (NM_001127697)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 215 of Ataxin 3|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens ataxin 3 (ATXN3), transcript variant e|
|AT3; ATX3; JOS; MJD; MJD1; SCA3|
Entrez Gene 4287 Human
Entrez Gene 110616 Mouse
|Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is the cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]|
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A: U87-MG (anti-ATXN3 antibody diluted at 1:1000)
A: mouse brain (anti-ATXN3 antibody diluted at 1:500)
Immunohistochemical analysis of paraffin-embedded H661 xenograft, using Ataxin 3(anti-ATXN3 antibody) antibody at 1:500 dilution.