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Home Antibody All anti-ATXN3 antibodies

Anti-ATXN3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308320
  • Rabbit Polyclonal antibody to Ataxin 3 (ataxin 3)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC432176) , 20ug Explanation
100ul 325 3-7 Days
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WB(2)
IHC(1)
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Also for ATXN3 (NM_001127697)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 245 of Ataxin 3 (Uniprot ID#P54252)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Pig, Rat, Bovine) Concentration0.73mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:10000
Predicted MW Explanation 42kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Pig (99%), Rat (96%), Bovine (98%)

Reference Data

Target NameHomo sapiens ataxin 3 (ATXN3), transcript variant e
Alternative NameAT3; ATX3; JOS; MJD; MJD1; SCA3
Database LinkNP_001121169
Entrez Gene 4287 Human
Entrez Gene 110616 Mouse
Entrez Gene 60331 Rat
FunctionMachado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is the cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Ataxin 3 antibody detects Ataxin 3 protein by western blot analysis. Mouse tissue extracts (50 ug) was separated by 10 % SDS-PAGE, and blotted with Ataxin 3 antibody (TA308320) diluted by 1:500
WB Image
Ataxin 3 antibody detects Ataxin 3 protein by western blot analysis. 293T mock transfected (-) or transfected with a construct expressing human Ataxin 3 (+). 10 % SDS-PAGE. Ataxin 3 antibody (TA308320) dilution: 1:5000
IHC Image
Immunohistochemical analysis of paraffin-embedded H661 xenograft, using Ataxin 3(TA308320) antibody at 1:500 dilution.

 

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