Home Antibody All anti-HLA-DMA antibodies
Also for HLA-DMA (NM_006120)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 52 and 245 of HLA-DMA|
|Human (Predicted: Bovine)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Bovine (83%)
|Homo sapiens major histocompatibility complex, class II, DM alpha (HLA-DMA)|
|D6S222E; DMA; HLADM; RING6|
Entrez Gene 3108 Human
|HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq]|
|Transmembrane Cell adhesion molecules (CAMs)Antigen processing and presentationType I diabetes mellitusAsthmaAutoimmune thyroid diseaseSystemic lupus erythematosusMore Pathways >> |
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HLA-DMA antibody detects HLA-DMA protein by Western blot analysis. A. 30 ug Jurkat whole cell lysate/extract. B. 30 ug Raji whole cell lysate/extract. 12 % SDS-PAGE. HLA-DMA antibody (TA308310) dilution: 1:500
Sample (30 ug of whole cell lysate). A: Hela. 12% SDS PAGE. TA308310 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded Breast ca, using HLA-DMA(TA308310) antibody at 1:250 dilution.