Home Antibody All anti-HLA-DMA antibodies
Also for HLA-DMA (NM_006120)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 52 and 255 of HLA-DMA|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens major histocompatibility complex, class II, DM alpha (HLA-DMA)|
|D6S222E; DMA; HLADM; RING6|
|HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq]|
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A: Hela (anti-HLA-DMA antibody diluted at 1:1000)