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Home Antibody All anti-HLA-DMA antibodies

Anti-HLA-DMA Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308310
  • Rabbit polyclonal antibody to HLA-DMA (major histocompatibility complex, class II, DM alpha)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC416850) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for HLA-DMA (NM_006120)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 52 and 255 of HLA-DMA
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens major histocompatibility complex, class II, DM alpha (HLA-DMA)
Alternative NameD6S222E; DMA; HLADM; RING6
Database LinkNP_006111
FunctionHLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq]
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
A: Hela (anti-HLA-DMA antibody diluted at 1:1000)

 

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