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Home Antibody All anti-NDUFA5 antibodies

Anti-NDUFA5 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308306
  • Rabbit Polyclonal antibody to NDUFA5 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417602) , 20ug Explanation
100ul 325 3-7 Days
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WB(2)
IHC(1)
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Also for NDUFA5 (NM_005000)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 116 of NDUFA5 (Uniprot ID#Q16718)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Chimpanzee) Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 13kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Chimpanzee (100%)

Reference Data

Target NameHomo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (NDUFA5), transcript variant 1
Alternative NameB13; CI-13kB; CI-13KD-B; NUFM; UQOR13
Database LinkNP_004991
Entrez Gene 4698 Human
Entrez Gene 68202 Mouse
FunctionThe human NDUFA5 gene codes for the B13 subunit of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. The high degree of conservation of NDUFA5 extending to plants and fungi indicates its functional significance in the enzyme complex. The protein localizes to the inner mitochondrial membrane as part of the 7 component-containing, water soluble "iron-sulfur protein" (IP) fraction of complex I, although its specific role is unknown. It is assumed to undergo post-translational removal of the initiator methionine and N-acetylation of the next amino acid. The predicted secondary structure is primarily alpha helix, but the carboxy-terminal half of the protein has high potential to adopt a coiled-coil form. The amino-terminal part contains a putative beta sheet rich in hydrophobic amino acids that may serve as mitochondrial import signal. Related pseudogenes have also been identified on four other chromosomes. [provided by RefSeq]
Related Pathway Oxidative phosphorylationMetabolic pathwaysAlzheimer's diseaseParkinson's diseaseHuntington's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (50 ug of whole cell lysate). A: mouse brain. 15% SDS PAGE. TA308306 diluted at 1:1000.
WB Image
Sample (30 ug of whole cell lysate). A: Hep G2 . 15% SDS PAGE. TA308306 diluted at 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using NDUFA5(TA308306) antibody at 1:500 dilution.

 

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