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Home Antibody All anti-RASA3 antibodies

Anti-RASA3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308271
  • Rabbit polyclonal antibody to RASA3 (RAS p21 protein activator 3)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416017) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
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Also for RASA3 (NM_007368)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 746 and 834 of RASA3 (Uniprot ID#Q14644)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Xenopus laevis, Chicken, Bovine) Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 96kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (87%), Xenopus laevis (93%), Chicken (100%), Bovine (87%)

Reference Data

Target NameHomo sapiens RAS p21 protein activator 3 (RASA3)
Alternative NameGAP1IP4BP; GAPIII
Database LinkNP_031394
Entrez Gene 22821 Human
Entrez Gene 19414 Mouse
FunctionThe protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane. [provided by RefSeq]
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: H1299. 7.5% SDS PAGE. RASA3 antibody. TA308271 diluted at 1:1000.

 

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