Home Antibody All anti-MAP2K1IP1 antibodies
Also for MAP2K1IP1 (NM_021970)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 102 of human MAP2K1IP1|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 (LAMTOR3), transcript variant 1|
|MAP2K1IP1; MAPBP; MAPKSP1; MP1; PRO0633; Ragulator3|
|This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Multiple transcript variants are expressed by this gene, but only one variant is thought to express a protein. [provided by RefSeq]|
MAPK signaling pathway
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Sample (30 ug of whole cell lysate) A: 293T 1(anti-MAP2K1IP1 antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using MP1(anti-MAP2K1IP1 antibody) antibody at 1:500 dilution.