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Home Antibody All anti-MAP2K1IP1 antibodies

Anti-MAP2K1IP1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308268
  • Rabbit Polyclonal antibody to MP1 (MAPK scaffold protein 1)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC411845) , 20ug Explanation
100ul 325 3-7 Days
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WB(3)
IHC(1)
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Also for MAP2K1IP1 (NM_021970)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 124 of MP1 (Uniprot ID#Q9UHA4)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Bovine, Xenopus tropicalis) Concentration0.88mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 14kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (97%), Bovine (99%), Xenopus tropicalis (85%)

Reference Data

Target NameHomo sapiens late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 (LAMTOR3), transcript variant 1
Alternative NameMAP2K1IP1; MAPBP; MAPKSP1; MP1; PRO0633; Ragulator3
Database LinkNP_068805
Entrez Gene 8649 Human
Entrez Gene 56692 Mouse
FunctionThis gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Multiple transcript variants are expressed by this gene, but only one variant is thought to express a protein. [provided by RefSeq]
Related PathwayDruggable Genome MAPK signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
MP1 antibody detects MP1 protein by Western blot analysis. A. 30 ug Rat2 whole cell lysate/extract. 15 % SDS-PAGE. MP1 antibody (TA308268) dilution: 1:1000
WB Image
MP1 antibody detects MP1 protein by Western blot analysis. A. 30 ug Neuro2A whole cell lysate/extract. B. 30 ug Raw264.7 whole cell lysate/extract. C. 30 ug C2C12 whole cell lysate/extract. 15 % SDS-PAGE. MP1 antibody (TA308268) dilution: 1:1000
WB Image
Sample (30 ug of whole cell lysate). A: 293T. 15% SDS PAGE. TA308268 diluted at 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using MP1(TA308268) antibody at 1:500 dilution.

 

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