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Also for RAE1 (NM_001015885)
|Synthetic peptide corresponding to a region within amino acids 307 and 368 of RAE1 (Uniprot ID#P78406)|
|Human (Predicted: Mouse, Rat, Zebrafish, Xenopus laevis, Xenopus Tropicalis, Pig, Bovine)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Xenopus Tropicalis (100%), Pig (100%), Bovine (100%)
|Homo sapiens ribonucleic acid export 1 (RAE1), transcript variant 2|
|dJ481F12.3; dJ800J21.1; MIG14; Mnrp41; MRNP41|
Entrez Gene 8480 Human
Entrez Gene 66679 Mouse
Entrez Gene 362281 Rat
|Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
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Sample(30 ug of whole cell lysate). A:HeLa S3. 12% SDS PAGE. TA308264 diluted at 1:1500
RAE1 antibody [C3], C-term detects RAE1 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: RAE1 protein stained by RAE1 antibody [C3], C-term (TA308264) diluted at 1:500. Blue: