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Home Antibody All anti-RAE1 antibodies

Anti-RAE1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308264
  • Rabbit polyclonal antibody to RAE1 (RAE1 RNA export 1 homolog (S. pombe))
100ul 325 3-7 Days
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WB(1)
IF(1)
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Also for RAE1 (NM_001015885)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 307 and 368 of RAE1 (Uniprot ID#P78406)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Zebrafish, Xenopus laevis, Xenopus Tropicalis, Pig, Bovine) Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 41kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Xenopus Tropicalis (100%), Pig (100%), Bovine (100%)

Reference Data

Target NameHomo sapiens ribonucleic acid export 1 (RAE1), transcript variant 2
Alternative NamedJ481F12.3; dJ800J21.1; MIG14; Mnrp41; MRNP41
Database LinkNP_001015885
Entrez Gene 8480 Human
Entrez Gene 66679 Mouse
Entrez Gene 362281 Rat
FunctionMutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug of whole cell lysate). A:HeLa S3. 12% SDS PAGE. TA308264 diluted at 1:1500
IF Image
RAE1 antibody [C3], C-term detects RAE1 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: RAE1 protein stained by RAE1 antibody [C3], C-term (TA308264) diluted at 1:500. Blue:

 

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