Anti-GBA Antibody,

Also for GBA (NM_001005750)

OriGene Data

Immunogen	Recombinant protein fragment contain a sequence corresponding to a region within amino acids 352 and 529 of Human GBA
Clone Name		Isotype	IgG
Species Reactivity	Human	Concentration	0.82mg/ml
Guaranteed Application *	WB, IHC, IF	Suggested Dilutions	WB:1:500-1:3000; IHC:1:100; IF:1:100-1:500;
Buffer	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification	Purified by antigen-affinity chromatography. (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens glucosidase, beta; acid (includes glucosylceramidase) (GBA), transcript variant 5
Alternative Name	GBA1; GCB; GLUC; GCB; GLUC; D-glucosyl-N-acylsphingosine glucohydrolase; OTTHUMP00000033992; OTTHUMP00000033993; glucocerebrosidase; glucocerebrosidase (alt.); lysosomal glucocerebrosidase; glucosidase, beta; acid (includes glucosylceramidase)
Database Link	NP_001005750
Function	This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]
Related Pathway

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WB Image

Sample(30 ug of whole cell lysate) A:HepG2 (anti-GBA antibody diluted at 1:500)

IHC Image

Immunohistochemical analysis of paraffin-embedded Lung CA, using GBA(anti-GBA antibody) antibody at 1:100 dilution.

IF Image

Immunofluorescence analysis of methanol-fixed HeLa, using GBA(anti-GBA antibody) antibody at 1:100 dilution.

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-GBA Antibody

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data