Home Antibody All anti-IDH3G antibodies
Also for IDH3G (NM_004135)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 257 of Human IDH3G|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens isocitrate dehydrogenase 3 (NAD+) gamma (IDH3G), transcript variant 1|
Entrez Gene 3421 Human
Entrez Gene 15929 Mouse
|Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined. [provided by RefSeq]|
| Citrate cycle (TCA cycle)Metabolic pathways|
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A: A431 (anti-IDH3G antibody diluted at 1:1000)
A: Mouse brain (anti-IDH3G antibody diluted at 1:1000)