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Home Antibody All anti-MTAP antibodies

Anti-MTAP Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308228
  • Rabbit Polyclonal antibody to MTAP (methylthioadenosine phosphorylase)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419313) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for MTAP (NM_002451)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 283 of MTAP (Uniprot ID#Q13126)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Rhesus Monkey) Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 31kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rhesus Monkey (100%)

Reference Data

Target NameHomo sapiens methylthioadenosine phosphorylase (MTAP)
Alternative NameBDMF; c86fus; DMSFH; DMSMFH; HEL-249; LGMBF; MSAP
Database LinkNP_002442
Entrez Gene 4507 Human
Entrez Gene 66902 Mouse
Entrez Gene 709020 Monkey
FunctionThis gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq]
Related PathwayDruggable Genome Cysteine and methionine metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (50 ug of whole cell lysate). A: mouse liver. 12% SDS PAGE. TA308228 diluted at 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded SAS xenograft , using MTAP(TA308228) antibody at 1:500 dilution.

 

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