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Home Antibody All anti-DEDD antibodies

Anti-DEDD Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308217 Rabbit polyclonal antibody to DEDD (death effector domain containing) 100ul $325 3-7 Days
LC421815 DEDD HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for DEDD (NM_001039712)
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OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 129 and 223 of DEDD (Uniprot ID#O75618)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Xenopus laevis, Rhesus Monkey, Bovine) Concentration0.42mg/ml
Guaranteed Application *WB, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 37kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (100%), Rat (100%), Xenopus laevis (100%), Rhesus Monkey (100%), Bovine (100%)

Reference Data

Target NameHomo sapiens death effector domain containing (DEDD), transcript variant 4
Alternative NameCASP8IP1; DEDD1; DEFT; FLDED1; KE05
Database LinkNP_001034801
Entrez Gene 9191 Human
Entrez Gene 21945 Mouse
Entrez Gene 83631 Rat
Entrez Gene 719875 Monkey
FunctionThis gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: Raji. 10% SDS PAGE. TA308217 diluted at 1:1000.
Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using DEDD(TA308217) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:2500.


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