Home Antibody All anti-DEDD antibodies
Also for DEDD (NM_001039712)
|Synthetic peptide corresponding to a region within amino acids 129 and 223 of DEDD (Uniprot ID#O75618)|
|Human (Predicted: Mouse, Rat, Xenopus laevis, Rhesus Monkey, Bovine)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (100%), Rat (100%), Xenopus laevis (100%), Rhesus Monkey (100%), Bovine (100%)
|Homo sapiens death effector domain containing (DEDD), transcript variant 4|
|CASP8IP1; DEDD1; DEFT; FLDED1; KE05|
Entrez Gene 9191 Human
Entrez Gene 21945 Mouse
Entrez Gene 83631 Rat
Entrez Gene 719875 Monkey
|This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
|Transcription FactorsDruggable Genome |
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Sample (30 ug of whole cell lysate). A: Raji. 10% SDS PAGE. TA308217 diluted at 1:1000.
Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using DEDD(TA308217) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:2500.