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Home Antibody All anti-CYP24A1 antibodies

Anti-CYP24A1 Antibody

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Specifications Citations (1) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308204
  • Rabbit polyclonal antibody to CYP24A1 (cytochrome P450, family 24, subfamily A, polypeptide 1)
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for CYP24A1 (NM_001128915)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 241 and 514 of CYP24A1 (Uniprot ID#Q07973)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB:1:500-1:3000
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: mouse (87%), Rat (88%)

Reference Data

Target NameHomo sapiens cytochrome P450, family 24, subfamily A, polypeptide 1 (CYP24A1), transcript variant 2
Alternative NameCP24; CYP24; HCAI; P450-CC24
Database LinkNP_001122387
Entrez Gene 1591 Human
Entrez Gene 13081 Mouse
Entrez Gene 25279 Rat
FunctionThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30ug whole cell lysate). A: 293T. B: A431 . C: H1299. D: HeLa S3 . E: Hep G2 . F: MOLT4 . G: Raji . 7.5% SDS PAGE. TA308204 diluted at 1:3000
IHC Image
CYP24A1 antibody detects CYP24A1 protein at cytosol on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. CYP24A1 antibody (TA308204) dilution: 1:500.

 

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