Home Antibody All anti-ARG1 antibodies
Also for ARG1 (NM_000045)
|Recombinant fragment corresponding to a region within amino acids 1 and 322 of Arginase I (Uniprot ID#P05089)|
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:1000-1:50000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens arginase 1 (ARG1), transcript variant 2|
|OTTHUMP00000017209; arginase 1; liver-type arginase; type I arginase; arginase, liver|
Entrez Gene 383 Human
Entrez Gene 11846 Mouse
| Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. [provided by RefSeq]|
|Druggable Genome Arginine and proline metabolismMetabolic pathways|
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Sample (20 ug of whole cell lysate). A: mouse liver. 10% SDS PAGE. TA308162 diluted at 1:50000.
Arginase 1 antibody detects ARG1 protein by Western blot analysis. A. 30 ug HepG2 whole cell lysate/extract. 10 % SDS-PAGE. Arginase 1 antibody (TA308162) dilution: 1:1000
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using arginase I (TA308162) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using arginase I (TA308162) antibody at 1:200 dilution.