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Home Antibody All anti-RAP1A antibodies

Anti-RAP1A Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308128 Rabbit polyclonal antibody to RAP1A (RAP1A, member of RAS oncogene family) 100ul $325 3-7 Days
LC423240 RAP1A HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRecombinant fragment contain a sequence corresponding to a region within amino acids 1 and 134 of RAP1 (Uniprot ID#P62834)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Rhesus Monkey, Bovine) Concentration0.53mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 21kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (100%)

Reference Data

Target NameHomo sapiens RAP1A, member of RAS oncogene family (RAP1A), transcript variant 1
Alternative NameC21KG; G-22K; KREV-1; KREV1; RAP1; SMGP21
Database LinkNP_001010935
Entrez Gene 5906 Human
Entrez Gene 109905 Mouse
Entrez Gene 295347 Rat
Entrez Gene 704404 Monkey
FunctionThe product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq]
Related PathwayDruggable Genome MAPK signaling pathwayChemokine signaling pathwayFocal adhesionLeukocyte transendothelial migrationLong-term potentiationNeurotrophin signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: Molt-4 . 12% SDS PAGE. RAP1A antibody. TA308128 diluted at 1:1000.


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