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Home Antibody All anti-HUS1 antibodies

Anti-HUS1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308100 Rabbit polyclonal antibody to HUS1 (HUS1 checkpoint homolog (S. pombe)) 100ul $325 In Stock
LC401435 HUS1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 273 of HUS1 (Uniprot ID#O60921)
Clone Name IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 32kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens HUS1 checkpoint clamp component (HUS1), transcript variant 1
Alternative NamehHUS1; hHUS1
Database LinkNP_004498
Entrez Gene 3364 Human
FunctionThe protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. [provided by RefSeq]
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HUS1 antibody detects HUS1 protein by Western blot analysis. A. 30 ug C8D30 whole cell lysate/extract. 12 % SDS-PAGE. HUS1 antibody (TA308100) dilution: 1:1000

WB Image
Sample (30 ug of whole cell lysate). A: 293T. 12% SDS PAGE. TA308100 diluted at 1:1000.

IHC Image
Immunohistochemical analysis of paraffin-embedded CA922 xenograft , using HUS1(TA308100) antibody at 1:500 dilution.

IHC Image
HUS1 antibody detects HUS1 protein at cytosol and nucleus on rat fore brain by immunohistochemical analysis. Sample: Paraffin-embedded rat fore brain. HUS1 antibody (TA308100) dilution: 1:500.

IHC Image
HUS1 antibody detects HUS1 protein at cytosol and nucleus on mouse lymph node by immunohistochemical analysis. Sample: Paraffin-embedded mouse lymph node. HUS1 antibody (TA308100) dilution: 1:500.


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